Fertility Research & Clinical Evidence
Natural Conception
Evidence-Based Integrative Medicine: Prior to Conception: The Role of an Acupuncture Protocol in Improving Women's Reproductive Functioning Assessed by a Pilot Pragmatic Randomised Controlled Trial
Evidence-Based Complementary and Alternative Medicine: Acupuncture as Treatment for Female Infertility: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
American Journal of Clinical Nutrition: Dietary fatty acid intakes and the risk of ovulatory infertility
IUI/IVF Support
Reproductive Biomedicine online: The impact of food intake and social habits on embryo quality
Fertility and Sterility: Comparison of Stress Levels in Women Undergoing Single Versus Multiple Acupuncture Session Prior to Embryo Transfer
Fertility and Sterility: Live births in women who integrate whole systems traditional Chinese medicine with IVF: does age matter?
Reproductive Biomedicine online: Impact of whole systems traditional Chinese medicine on in-vitro fertilization outcomes
Acupuncture in Medicine: Journal of the British Medical Acupuncture Society: Influence of acupuncture on the outcomes of in vitro fertilisation when embryo implantation has failed: a prospective randomised controlled clinical trial
Fertility and Sterility: Influence of acupuncture on the pregnancy rate in patients who undergo assisted reproduction therapy
ScienceDirect: Acupuncture and Chinese herbal treatment for women undergoing intrauterine insemination
Complementary Therapies in Clinical Practice: The relationship between perceived stress, acupuncture, and pregnancy rates among IVF patients: A pilot study
British Medical Journal: Effects of acupuncture on rates of pregnancy and live birth among women undergoing in vitro fertilization: systematic review and meta-analysis
Annals of Medicine: Clinical evidence of coenzyme Q10 pretreatment for women with diminished ovarian reserve undergoing IVF/ICSI: a systematic review and meta-analysis
Human Reproduction: Effects of female and male smoking on success rates of IVF and gamete intra-Fallopian transfer
Frontiers in Reproductive Health: Melatonin improved the outcomes of women with ART: a systematic review and meta-analysis of randomized trials
Journal of Ovarian Reseach: Myo-inositol therapy for poor-responders during IVF: a prospective controlled observational trial
Archives of Gynecology and Obstetrics: Myo-inositol is a promising treatment for the prevention of ovarian hyperstimulation syndrome (OHSS): an animal study
Middle East Fertility Society Journal: Clomiphene-acetyl cysteine combination as a new protocol to a friendly IVF cycle
Human Reproduction: Adjuvant L-arginine treatment for in-vitro fertilization in poor responder patients
High FSH/Diminished Ovarian Reserve
Acupuncture in Medicine: Journal of the British Medical Acupuncture Society: Electroacupuncture for reproductive hormone levels in patients with diminished ovarian reserve: a prospective observational study
Perimenopause: Association between serum 25-hydroxyvitamin D and ovarian reserve in premenopausal women
Human Fertility: Influence of nutrition on the decline of ovarian reserve and subsequent onset of natural menopause
Evidence-Based Complementary and Alternative Medicine: Effect of acupuncture on premature ovarian failure
Annals of Medicine: Clinical evidence of coenzyme Q10 pretreatment for women with diminished ovarian reserve undergoing IVF/ICSI: a systematic review and meta-analysis
Donor Cycles
Reproductive Biomedicine Online: Impact of whole systems traditional Chinese medicine on in-vitro fertilization outcomes
Journal of Alternative and Complementary Medicine: Acupuncture and in vitro fertilization: a retrospective chart review
Fertility and Sterility: Influence of vitamin D levels on in vitro fertilization outcomes in donor-recipient cycles
Pregnancy Loss and Pregnancy Support
Reproductive Biomedicine Online: N-acetyl Cysteine for Treatment of Recurrent Unexplained Pregnancy Loss
BMC Complementary and Alternative Medicine: Acupuncture as a therapeutic treatment option for threatened miscarriage
Obstetrics & Gynecology: Acupuncture for Depression During Pregnancy: A Randomized Controlled Trial
American Journal of Obstetrics and Gynecology: Maternal caffeine consumption during pregnancy and the risk of miscarriage: a prospective cohort study
The American Journal Of Clinical Nutrition: Vitamin D insufficiency is associated with increased risk of first-trimester miscarriage in the Odense Child Cohort
Endometriosis
European Journal of Obstetrics, Gynecology and Reproductive Biology: Is acupuncture in addition to conventional medicine effective as pain treatment for endometriosis? A random controlled cross-over trial
Journal of Pediatric and Adolescent Gynecology: Japanese-style acupuncture for endometriosis-related pelvic pain in adolescents and young women: results of a randomized sham-controlled trial
Expert Opinion on Therapeutic Targets: Targeting oxidative stress to treat endometriosis
Dove Press: Is acupuncture effective of the treatment of pain in endometriosis?
Frontiers in Microbiology: Role of the gut microbiota in the pathogenesis of endometriosis: a review
Human Reproduction Open: Microbiome dysbiosis and endometriosis: a systematic scoping review of current literature and knowledge gaps
PCOS
Molecular and Cellular Endocrinology: Circulating gonadotropins and ovarian adiponectin system are modulated by acupuncture independently of sex steroid or β-adrenergic action in a female hyperandrogenic rat model of polycystic ovary syndrome
American Journal for Physiology, Endocrinology and Metabolism: Acupuncture for ovulation induction in polycystic ovary syndrome: a randomized controlled trial
NCBI: Current evidence of acupuncture on polycystic ovarian syndrome
Journal of Complementary and Alternative Medicine: Effectiveness of abdominal acupuncture for patients with obesity-type polycystic ovary syndrome: a randomized controlled trial
Journal of Biological Regulators and homeostatic Agents: Effect of myo-inositol and alpha-lipoic acid on oocyte quality in polycystic ovary syndrome non-obese women undergoing in vitro fertilization: a pilot study
PCOS One: The Gut Microbiome Is Altered in a Letrozole-Induced Mouse Model of Polycystic Ovary Syndrome
Fertility and Sterility: N-acetyl-cysteine is a novel adjuvant to clomiphene citrate in clomiphene citrate–resistant patients with polycystic ovary syndrome
The Journal of Obstetrics and Gynecologic Research: Chromium picolinate reduces insulin resistance in polycystic ovary syndrome: Randomized controlled trial
Male factor
Spermatogenesis: Electroacupuncture enhances spermatogenesis in rats after scrotal heat treatment
ScienceDirect: Zinc Levels in Seminal Plasma are Associated with Sperm Quality in Fertile and Infertile Men
NCBI: Does acupuncture treatment affect sperm density in males with very low sperm count? A pilot study
Reproductive Biology and Endocrinology: The importance of the one carbon cycle nutritional support in human male fertility: a preliminary clinical report
F&S Reviews: Sperm DNA fragmentation and infertility: a narrative review
Dysmenorrhea
National Center for Biotechnology Information (NCBI): Controlled acupuncture in the treatment of patients with primary dysmenorrhea
National Center for Biotechnology Information (NCBI): Efficacy of Acupuncture in the Management of Primary Dysmenorrhea
National Center for Biotechnology Information (NCBI): Acupuncture for Primary Dysmenorrhea: A Potential Mechanism from an Anti-Inflammatory Perspective
PMS/PMDD
National Center for Biotechnology Information (NCBI): Effects and treatment methods of acupuncture and herbal medicine for premenstrual syndrome/premenstrual dysphoric disorder
National Center for Biotechnology Information (NCBI): Acupuncture for Premenstrual Syndrome at Different Intervention Time
National Center for Biotechnology Information (NCBI): Altered fractional amplitude of low-frequency fluctuation in women with premenstrual syndrome via acupuncture
National Center for Biotechnology Information (NCBI): Altered Brain Regional Homogeneity Following Electro-Acupuncture Stimulation in Women With Premenstrual Syndrome
Perimenopause and Menopause Support
National Center for Biotechnology Information (NCBI): Electroacupuncture versus Sham Acupuncture for Perimenopausal Insomnia
National Center for Biotechnology Information (NCBI): Acupuncture-adjuvant therapies for treating perimenopausal depression
National Center for Biotechnology Information (NCBI): Acupuncture in Menopause
JAMA Internal Medicine: Acupuncture in Menopause (AIM) study: a pragmatic, randomized controlled trial
National Center for Biotechnology Information (NCBI): Efficacy of a standardized acupuncture approach for women with bothersome menopausal symptoms
Nervous System & Vagal Regulation
Biological Psychology: Polyvagal Theory: Current Status, Clinical Applications, and Future Directions https://pubmed.ncbi.nlm.nih.gov/40735382/
Frontiers in Behavioral Neuroscience: Polyvagal theory: a journey from physiological observation to neural innervation and clinical insight https://pmc.ncbi.nlm.nih.gov/articles/PMC12479538/
Developmental Psychobiology: An in-depth analysis of the polyvagal theory in light of current findings in neuroscience and clinical research https://pubmed.ncbi.nlm.nih.gov/38388187/
Sleep & Circadian Rhythm
BMC Women's Health: Sleep disturbances and female infertility: a systematic review https://pmc.ncbi.nlm.nih.gov/articles/PMC11660991/
Frontiers in Reproductive Health: Melatonin improved the outcomes of women with ART: a systematic review and meta-analysis of randomized trials https://www.frontiersin.org/journals/reproductive-health/articles/10.3389/frph.2025.1680984/full
Frontiers in Endocrinology: Melatonin improves fertilization rate in assisted reproduction: Systematic review and meta-analysis https://pmc.ncbi.nlm.nih.gov/articles/PMC11265587/
Stress, HPA Axis & Cortisol
Frontiers in Endocrinology: Infertility and cortisol: a systematic review https://pmc.ncbi.nlm.nih.gov/articles/PMC10344356/
Journal of Psychosomatic Obstetrics and Gynaecology: The relationship between psychological stress and ovulatory disorders and its molecular mechanisms: a narrative review https://www.tandfonline.com/doi/full/10.1080/0167482X.2024.2418110
International Journal of Molecular Medicine: Impact of psychological stress on ovarian function https://www.spandidos-publications.com/10.3892/ijmm.2024.5475
Gut Microbiome & Reproductive Health
Microbiome: From gut to gamete: how the microbiome influences fertility and preconception health https://pmc.ncbi.nlm.nih.gov/articles/PMC12465865/
Frontiers in Cellular and Infection Microbiology: The gut microbiota: emerging biomarkers and potential treatments for infertility-related diseases https://pubmed.ncbi.nlm.nih.gov/39391885/
Reproductive Biology and Endocrinology: Gut Microbiome Dysbiosis and Its Impact on Reproductive Health: Mechanisms and Clinical Applications https://pmc.ncbi.nlm.nih.gov/articles/PMC12195147/
Mitochondrial Health & Egg Quality
Annals of Medicine: Clinical evidence of coenzyme Q10 pretreatment for women with diminished ovarian reserve undergoing IVF/ICSI: a systematic review and meta-analysis https://pubmed.ncbi.nlm.nih.gov/39129455/
Aging Cell: Coenzyme Q10 restores oocyte mitochondrial function and fertility during reproductive aging https://pubmed.ncbi.nlm.nih.gov/26111777/
Fertility and Sterility: Antioxidant intervention promotes cell survival and balance within the ovary and improved IVF outcomes https://www.fertstert.org/article/S0015-0282(18)31493-6/fulltext
Somatic Healing & Trauma
Journal of Traumatic Stress: Somatic Experiencing for Posttraumatic Stress Disorder: A Randomized Controlled Outcome Study https://pubmed.ncbi.nlm.nih.gov/28585761/
European Journal of Psychotraumatology: Somatic experiencing: effectiveness and key factors of a body-oriented trauma therapy: a scoping literature review https://pmc.ncbi.nlm.nih.gov/articles/PMC8276649/
European Journal of Psychotraumatology: A randomized controlled trial of brief Somatic Experiencing for chronic low back pain and comorbid post-traumatic stress disorder symptoms https://pubmed.ncbi.nlm.nih.gov/28680540/